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The elimination rate constant ''K'' is a value used in pharmacokinetics to describe the rate at which a drug is removed from the system. It is often abbreviated ''K'' or ''K''''e''. It is equivalent to the fraction of a substance that is removed per unit time measured at any particular instant and has units of T−1. This can be expressed mathematically with the differential equation :, where is the blood plasma concentration of drug in the system at a given point in time , is an infinitely small change in time, and is the concentration of drug in the system after the infinitely small change in time. The solution of this differential equation is useful in calculating the concentration after the administration of a single dose of drug via IV bolus injection: : *''Ct'' is concentration after time ''t'' *''C0'' is the initial concentration (''t''=0) *''K'' is the elimination rate constant ==Sample values and equations== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「elimination rate constant」の詳細全文を読む スポンサード リンク
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